## Research Associate in statistical bioinformatics

Reliable interpretation of genomic and neurological information makes unprecedented demands for innovations in statistical methodology and its application to biological systems. This unique opportunity drives research at the Statomics Lab of the Ottawa Institute of Systems Biology (http://www.statomics.com). The Statomics Lab seeks a Research Associate who will collaboratively develop and apply novel methods of statistical inference to attack current problems in analyzing transcriptomics, proteomics, metabolomics, lipidomics, genome-wide-association data, and/or neuroscience data. The successful candidate will also play a key role in the mentorship of junior members of the lab.

A thorough knowledge of computationally intensive statistics is essential, as is the ability to quickly develop reliable software implementing the statistical algorithms developed. A promising publication record, strong initiative, excellent communication skills, and reception of a PhD or equivalent doctorate in bioinformatics, computer science, mathematics, physics, statistics, any field of engineering, or an equally quantitative field are also absolutely necessary. The following qualities are desirable but not required: expertise in bootstrapping and/or constructing accurate confidence intervals; a working knowledge of biology; familiarly with R, S-PLUS, Mathematica, C, Fortran, and/or LaTeX; experience in a UNIX or Linux environment.

To apply, send a PDF CV that has contact information of three references to dbickel@uOttawa.ca, with “Research Associate” in the subject field of the message. In the message body, concisely present evidence that you meet each requirement for the position and describe your most significant papers and software packages with summaries of how you contributed to them. All applicants are thanked in advance; only those selected for further consideration will receive a response.

## Graduate studies in statistical lipidomics

Scientific breakthroughs from genome-sequencing projects brought the realization that reliable interpretation of the resulting information makes unprecedented demands for innovations in statistical methodology and its application to biological systems. This unique opportunity drives research at the Statomics Lab of the Ottawa Institute of Systems Biology (http://www.statomics.com). For the CIHR Training Program in Neurodegenerative Lipidomics, the Statomics Lab seeks a graduate student who will develop novel methods of statistical inference and collaboratively use them to discover or validate changes in lipid concentration.

Intellectual curiosity and high mathematical aptitude are essential, as is the ability to quickly code and debug computer programs. Strong self motivation, good communication skills, and a degree in bioinformatics, computer science, mathematics, physics, statistics, any field of engineering, or an equally quantitative field are also absolutely necessary. The following qualities are desirable but not required: coursework in computer science, numerical methods, numerical analysis, software engineering, statistics, and/or biology; familiarly with BUGS, R, S-PLUS, C, Fortran, and/or LaTeX; experience with UNIX or Linux.

To be considered, send a PDF CV that has your GPA and contact information of two references to dbickel0@uottawa.ca (without the zero) with “statistical lipidomics graduate student” in the Subject line of the message. In the message body, specify the graduate program in which you wish to take courses (either Biochemistry or Mathematics and Statistics) and the degree sought (MSc or PhD). Only those students selected for further consideration will receive a response.

## Postdoctoral training in Bayesian genomics

Scientific breakthroughs from genome-sequencing projects brought the realization that reliable interpretation of the resulting information makes unprecedented demands for innovations in statistical methodology and its application to biological systems. This unique opportunity drives research at the Statistical Inference and Computation in Genomics Laboratory of the Ottawa Institute of Systems Biology. The Statomics Lab (__http://www.statomics.com__) seeks a postdoctoral fellow who will collaboratively develop and apply Bayesian methods of statistical inference to attack current problems in analyzing transcriptomics, proteomics, metabolomics, lipidomics, and/or genome-wide association data.

A thorough knowledge of Bayesian theory is essential, as is the ability to quickly develop reliable software for approximating posterior distributions using complex models. Strong initiative, excellent communication skills, and reception of a PhD or equivalent doctorate in biostatistics, statistics, or a closely related field within the four years prior to the start date are also absolutely necessary. The following qualities are desirable but not required: expertise in one or more methods of frequentist inference; a working knowledge of biology; familiarly with R, S-PLUS, Mathematica, C, Fortran, and/or LaTeX; experience in a UNIX or Linux environment.

To apply, send a PDF CV that has contact information of three references to dbickel0@uottawa.ca (without the zero), with “Bayesian Genomics” and the year of your graduation or anticipated graduation in the subject field of the message. In the message body, concisely present evidence that you meet each requirement for the position and describe your most significant papers and software packages with summaries of how you contributed to them. All applicants are thanked in advance; only those selected for further consideration will receive a response.

## Postdoctoral training in model selection & applications

Scientific breakthroughs from genome-sequencing projects brought the realization that reliable interpretation of the resulting information makes unprecedented demands for advances in statistical methodology. As the complexity of genomic data sets drives innovative research in statistics, the Statistical Inference and Computation in Genomics (Statomics) Lab of the Ottawa Institute of Systems Biology attacks inferential challenges of importance to human health. The lab seeks a postdoctoral researcher who will collaboratively develop and apply statistical methods of model selection to solve current problems in analyzing transcriptomics, proteomics, metabolomics, lipidomics, and/or SNP-chip data.

A thorough knowledge of statistical theory is essential, as is the demonstrated ability to quickly and accurately implement complex statistical methods in software. Strong initiative, excellent communication skills, and reception of a PhD or equivalent doctorate in biostatistics, statistics, or a closely related field within the four years prior to the start date are also absolutely necessary. The following qualities are desirable but not required: expertise in one or more methods of frequentist model selection; knowledge of biology; familiarly with R, S-PLUS, C, Fortran, and/or LaTeX; experience in a UNIX or Linux environment.

To apply, send a PDF CV that has contact information of three references to dbickel0@uottawa.ca (without the zero), with “model selection & applications” and the year of your graduation or anticipated graduation in the subject field of the message. In the message body, concisely present evidence that you meet each requirement for the position and describe your most significant papers and software packages with summaries of how you contributed to them. All applicants are thanked in advance; only those selected for further consideration will receive a response.

## Postdoctoral Training in Statistical Genomics

Scientific breakthroughs from genome-sequencing projects brought the realization that reliable interpretation of the resulting information makes unprecedented demands for contemporaneous advances in computation and mathematical modeling. As the complexity of genomic data sets drives innovative statistics research, the new Statistical Inference and Computation in Genomics (Statomics) Lab of the Ottawa Institute of Systems Biology seeks a postdoctoral researcher who will collaboratively develop and apply statistical methods to solve current problems in analyzing and integrating gene-expression, proteomics, metabolomics, SNP, ChIP-chip, and/or clinical data. The lab is presently targeting inference in genome-wide association studies, bias reduction in estimated levels of gene expression, and validation of microarray predictions and will attack similar statistical and computational challenges of importance to genetics and functional genomics. The researcher’s background will complement that of any students and any postdoctoral researcher to be recruited to the Statomics Lab from the biomedical and computer science communities, creating an interdisciplinary environment for high impact on the biological sciences as well as on statistics.

Scientific creativity and a thorough knowledge of either Bayesian statistics or another likelihood-based inferential framework are essential, as is the demonstrated ability to quickly and accurately implement likelihood-based methods in software. Strong initiative, excellent communication skills, and reception of a PhD in statistics or a closely related field within the four years prior to the start date are also absolutely necessary. The following qualities are desirable but not required: exposure to the law of likelihood; knowledge of biology; familiarly with BUGS, R, S-PLUS, C, Fortran, and/or LaTeX; experience in a UNIX or Linux environment.

To apply, send a PDF CV that has contact information of three references to dbickel0@uottawa.ca (without the zero), with “likelihood postdoc” and the year of your graduation or anticipated graduation in the Subject line of the message; in the plaintext message body, concisely include evidence that you meet each requirement for the position and a description of your most significant papers and software packages with an explanation of your own contributions to them. Only those applicants selected for further consideration will receive a response.

## Graduate Student Stipends

Scientific breakthroughs from genome-sequencing projects brought the realization that reliable interpretation of the resulting information makes unprecedented demands for contemporaneous advances in computation and mathematical modeling. As the complexity of genomic data sets drives innovative statistics research, the new Statistical Inference and Computation in Genomics (Statomics) Lab of the Ottawa Institute of Systems Biology seeks MSc and PhD students who will develop and apply novel methodology and algorithms to solve current problems in analyzing gene-expression, proteomics, metabolomics, SNP, ChIP-chip, and/or phenotypic data. The lab is presently targeting inference in genome-wide association studies, estimation of levels of gene expression, and improvements in the repeatability of microarray results and will attack similar statistical and computational challenges of importance to genetics and functional genomics.

The OISB provides a highly collaborative research environment with ample opportunities to interact with leading experimental and computational biologists. In addition, each student’s background will complement that of any students and any postdoctoral researchers to be recruited to the Statomics Lab from the statistics, bioinformatics, and computer science communities, creating interdisciplinary synergism for making unique contributions to science.

Intellectual curiosity and high mathematical aptitude are essential, as is the ability to quickly code and debug computer programs. Canadian citizenship or permanent resident status, strong initiative, good communication skills, and a degree in bioinformatics, computer science, mathematics, physics, statistics, any field of engineering, or an equally quantitative field are also absolutely necessary. The following qualities are desirable but not required: coursework in computer science, numerical methods, numerical analysis, software engineering, statistics, and/or biology; familiarly with BUGS, R, S-PLUS, C, Fortran, and/or LaTeX; experience with UNIX or Linux.

Send a PDF CV that has your GPA and contact information of two references to dbickel0@uottawa.ca (without the zero) with “statistical bioinformatics graduate student” in the Subject line of the message and with your preferred graduate program (Biochemistry, Mathematics & Statistics, or Computer Science) and the degree sought (MSc or PhD) in the message body. Only those students selected for further consideration will receive a response.

## Statistical Bioinformatics Graduate Students

Scientific breakthroughs from genome-sequencing projects brought the realization that reliable interpretation of the resulting information makes unprecedented demands for contemporaneous advances in computation and mathematical modeling. As the complexity of genomic data sets drives innovative statistics research, the new Statistical Machine Learning in Functional Genomics (Statomics) Lab of the Ottawa Institute of Systems Biology seeks MSc and PhD students who will develop and apply novel methodology and algorithms to solve current problems in analyzing gene-expression, proteomics, metabolomics, SNP, ChIP-chip, and/or phenotypic data. The lab is presently targeting the inference of regulatory networks from multiple sources of information and improvements in the repeatability of microarray results and will attack similar statistics and machine learning challenges of importance to functional genomics.

The OISB provides a highly collaborative research environment with ample opportunities to interact with leading experimental and computational biologists; http://www.oisb.ca gives details. In addition, each student’s background will complement that of any students and any postdoctoral researchers to be recruited to the Statomics Lab from the Bayesian and machine learning communities, creating interdisciplinary synergism for making unique contributions to science. Students will have top-priority access to high-performance computing that enables parallelization of computationally complex methods.

Intellectual curiosity and high mathematical aptitude are essential, as is the ability to quickly code and debug computer programs. Canadian citizenship or permanent resident status, strong initiative, good communication skills, and a degree in bioinformatics, computer science, mathematics, physics, statistics, any field of engineering, or an equally quantitative field are also absolutely necessary. The following qualities are desirable but not required: coursework in computer science, numerical methods, numerical analysis, software engineering, statistics, and/or biology; familiarly with BUGS, R, S-PLUS, C, Fortran, and/or LaTeX; experience with UNIX or Linux.

To apply, send a PDF CV that has contact information of two references to dbickel0@uottawa.ca (without the zero) with “statistical bioinformatics graduate student” in the Subject line of the message. Only those applicants selected for further consideration will receive a response.